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The role of bioactive lipids in psoriasis.

21 April 2017

Psoriasis is a skin condition which can affect the body more generally. It is thought that the inflammation of the skin that occurs in psoriasis is associated with a change in lipids in the skin and in the blood. This study aims to look at lipids in skin and blood to see if they are different in people with psoriasis compared with people who do not have the condition. This may help in the development of new treatments


  • Inclusion criteria
  • - Volunteers with psoriasis that has been diagnosed by a dermatologist
  • - Onset of psoriasis at less than 40 years of age
  • - Male or female
  • - Aged 18 to 75 years
  • - Capable of giving informed consent
  • Exclusion criteria
  • - Skin problems (other than psoriasis)
  • - Incapable of giving informed consent
  • - Unwilling to unable to provide biopsy samples
  • - Severe medical condition
  • - Pregnancy or breast feeding
  • - Known allergy to anaesthetics such as lignocaine
  • - Use of statins
  • - Not on systematic therapy, including phototherapy, for psoriasis for at least 4 weeks and at least 12 weeks in the case of ustekinumab and secukinumab
  • - No active topical therapy to the biopsy sites for at least 2 weeks

Take part in this study


Ethical approval

This study has been reviewed by the collaborative study team at The University of Manchester. The study has also been reviewed and approved by the National Research Ethics Service and Research Ethic Committee 16/NW/0395.

About the researcher

PhD Researcher
BSc (Hons) Applied Chemical and Pharmaceutical Sciences

Contact researcher

Academic study

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