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The FruGut Study

20 October 2019

Are you aged 18-65 and have constipation? King’s college London need healthy volunteers for a 5-week study on diet and constipation. The aim of this study is to investigate the effect of the consumption of fruit products on outcomes related to constipation. We will ask you to consume fruit products, provide blood, urine and stool samples, complete diaries on diet, bowel habits and symptoms, and questionnaires. All study fruit products will be provided and £100 will be given upon completion.


  • Healthy people between 18-65 years old
  • People who have functional constipation
  • Body mass index between 18.5-29.9 kg/m2
  • Habitual low fibre intake
  • London residents (or live within 1 hour away from Waterloo Station and willing to travel for a minimum of 3 visits)
  • People with gut-related disorders (e.g., coeliac disease, Inflammatory Bowel Disease, diverticular disease) or other chronic disorders (e.g. renal, cardiac or pulmonary) will be excluded.
  • People who have taken certain medications recently known to affect gut motility (e.g. mebeverine, opiates), those who frequently use laxatives, have ongoing alcohol, drug or medication abuse
  • Those who frequently consume certain fruit products or dislike/have an intolerance or allergy to certain fruit products, and those who have had recent or extensive gut surgery will not be eligible
  • Pregnant and breastfeeding women will also be excluded.

Take part in this study


Ethical approval

This study has full ethical approval from the King's College London Research Ethics Committee. The approval was granted on 8/8/18.

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Academic study

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