CHAIN 1: Concurrent multi-organ responses to chronic inactivity
28 March 2024
Biological processes that underpin the relationship between physical activity levels and health are not clear. Addressing these knowledge gaps has been recognised as vital to assist scientists and medical doctors working in the fields of human chronic diseases and aging to help more adults reach old age in better health and maintain a good quality of life. Therefore, we wish to examine the effect of 6 months reduced activity by walking <4500 steps/day and increasing sitting time to 7hrs/day.
Requirements
- Overweight (BMI 25-29.9kg/m²) and aged between 55-65 years
- Not actively involved in exercise training and walk between 8,000 and 10,000 steps/day
- Have fewer than 6 hours of sitting down a day
Keywords
Ethical approval
This study has been ethically approved by the University of Nottingham's Faculty of Medicine and Health Sciences Research Ethics Committee (Ethics Reference Number: FHMS 103-0124)
