The CoolBAT study
19 January 2024
This study aims to increase knowledge of brown adipose tissue (BAT) in overweight individuals.
BAT produces heat by using the body’s white fat stores, and activation may help people avoid becoming overweight.
We are recruiting healthy volunteers aged 20-46 years with a BMI of 25-36 kg/m2.
Participants will wear cooling garments during two morning study visits. Undergoing magnetic resonance imaging and thermography before/after cooling.
Requirements
- You are willing and able to give informed consent for participation in the study.
- You are over 20 and under 46 years old
- Your BMI is between 25 and 36kg/m2 (see link to BMI calculator below)
- You are not pregnant or breastfeeding
- You are not taking any medications that may effect brown adipose tissue (eg: B blockers)
- You do not have any of the following medical conditions: cardiovascular disease, endocrine disorder, kidney disease, heart disease, or liver disease
- You do not have a family history of sudden cardiac death
- You are able to have an MRI – that means you must not have any metal in your body and are not claustrophobic
Keywords
Ethical approval
This study has been approved by the University of Nottingham Faculty of Medicine and Health Sciences Ethics Committee. FMHS rec no. 504-0322.
About the researcher
Principle Investigator - Professor Helen Budge
Senior Research Fellow - Dr Lindsay Robinson
